Preparation of poly(1,8-diaminonaphthalene)-based molecularly imprinted polymers for rhodamine onto ITO/Au electrodes and analytical application by surface-enhanced Raman spectroscopy (SERS)

A Nanosensor for TNT Detection Based on Molecularly Imprinted Polymers and Surface Enhanced Raman Scattering

We report on a new sensor strategy that integrates molecularly imprinted polymers (MIPs) with surface enhanced Raman scattering (SERS). The sensor was developed to detect the explosive, 2,4,6-trinitrotoluene (TNT). Micron thick films of sol gel-derived xerogels were deposited on a SERS-active surface as the sensing layer. Xerogels were molecularly imprinted for TNT using non-covalent interactio...

Analytical characterization and application of molecularly imprinted polymers

Molecularly Imprinted Polymers for Sample Preparation

The sample treatment/preparation steps involve any operation and manipulation of the samples prior to instrumental determination of the target compounds [1−3]. This is a critical step in the analytical process because the concentration of target analytes in the samples is frequently too low for quantification. Thus, the first step of the preparation protocol involves the exhaustive extraction/c...

Surface-enhanced Raman spectroscopy (SERS): nonlocal limitations

G. Toscano, S. Raza, S. Xiao, M. Wubs, A.-P. Jauho, S.I. Bozhevolnyi, and N.A. Mortensen Department of Photonics Engineering, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark Center for Electron Nanoscopy, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark Department of Micro and Nanotechnology, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark Institute of S...

Molecular Diagnosis of Plasma Phenylalanine in Neonates with Phenylketonuria Disease Using Biological Sensors Based on Surface-Enhanced Raman Spectroscopy (SERS)

In this study, silver nanoparticles were chemically synthesized and deposited on glass substrates using a reducing agent of sucrose, at 50°C. Different characterizations including atomic force microscopy (AFM), field emission scanning electron microscopy (FESEM), and Raman spectroscopy were obtained to study silvery substrates. Then, the silvery substrates were used as the SERS substrates to de...